Molecular biology lab

Seed biology – from lab to field

How to Grow a Computational Biology Lab

Start of the lab: 2007 Size of the lab: 16 Research field: Computational biology I began building my lab after having been selected to run an independent junior research group by the Max Planck Society at the Max Planck Institute for Informatics in Saarbrücken in 2007. At a meeting at Rutgers University that summer, I convinced a very good postdoc, Ben Adams, who was working in Japan by that ti...

IntelliEppi: Intelligent reaction monitoring and holistic data management system for the molecular biology lab

19 Daily alterations of routines and protocols create high, yet so far unmet demands for 20 intelligent reaction monitoring, quality control and data management in molecular biology 21 laboratories. To meet such needs, the “internet of things” is implemented here. We propose 22 an approach which combines direct tracking of lab tubes, reactions and racks with a 23 comprehensive data management s...

Using restriction mapping to teach basic skills in the molecular biology lab.

Digestion of DNA with restriction enzymes, calculation of volumes and concentrations of reagents for reactions, and the separation of DNA fragments by agarose gel electrophoresis are common molecular biology techniques that are best taught through repetition. The following open-ended, investigative laboratory exercise in plasmid restriction mapping allows students to gain technical expertise wh...

Systems biology versus molecular biology

Systems biology and molecular biology can answer the same question in quite different ways, and frequently the answers given by one sub-discipline seem no answer at all to the other. For many molecular biologists, a systemslevel explanation leaves them feeling that, until the underlying molecular mechanisms are known, the approach is hopelessly superficial. For systems biologists, on the other ...